xifendezhilizaixuduogongyebumenjinxing，rushipin
，xidiji，yaowuhenongyonghuaxuepinyigaishanfenmodewulihejixiexingneng
，liru，daxiao，jiegou，rongjiesulv，liudongxingweibingjianshaoyufenliyouguandewentihehuichendexingcheng。

造zao粒li作zuo為wei粒li度du增zeng大da的de一yi種zhong方fang法fa，在zai包bao括kuo藥yao物wu，食shi品pin，礦kuang物wu質zhi和he洗xi滌di劑ji在zai內nei的de許xu多duo行xing業ye中zhong是shi必bi不bu可ke少shao的de加jia工gong步bu驟zhou。特te別bie地di，在zai藥yao物wu工gong業ye中zhong製zhi造zao片pian劑ji之zhi前qian，使shi用yong造zao粒li作zuo為wei將jiang藥yao物wu和he載zai體ti顆ke粒li結jie合he在zai一yi起qi的de方fang法fa。盡jin管guan在zai製zhi造zao過guo程cheng中zhong這zhe一yi過guo程cheng非fei常chang重zhong要yao，但dan對dui造zao粒li的de基ji本ben機ji製zhi了le解jie甚shen少shao，擠ji壓ya造zao粒li設she備bei的de設she計ji和he優you化hua需xu要yao大da量liang的de時shi間jian和he資zi金jin。

此(ci)外(wai)，材(cai)料(liao)特(te)性(xing)或(huo)工(gong)藝(yi)參(can)數(shu)的(de)細(xi)微(wei)變(bian)化(hua)可(ke)能(neng)導(dao)致(zhi)顆(ke)粒(li)特(te)性(xing)和(he)藥(yao)物(wu)分(fen)布(bu)發(fa)生(sheng)重(zhong)大(da)變(bian)化(hua)。這(zhe)些(xie)是(shi)製(zhi)藥(yao)工(gong)業(ye)中(zhong)的(de)重(zhong)要(yao)問(wen)題(ti)，因(yin)為(wei)顆(ke)粒(li)的(de)機(ji)械(xie)性(xing)能(neng)對(dui)片(pian)劑(ji)強(qiang)度(du)和(he)溶(rong)解(jie)速(su)率(lv)具(ju)有(you)實(shi)質(zhi)性(xing)影(ying)響(xiang)，並(bing)且(qie)均(jun)勻(yun)的(de)顆(ke)粒(li)藥(yao)物(wu)分(fen)布(bu)對(dui)於(yu)實(shi)現(xian)片(pian)劑(ji)中(zhong)一(yi)致(zhi)的(de)藥(yao)物(wu)裝(zhuang)載(zai)是(shi)必(bi)不(bu)可(ke)少(shao)的(de)。